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| Ultimate™ ORFCard for Clone ID IOH6251 | |
|---|---|
| Gene Information | |
| Clone ID: | IOH6251 |
| Organism: | Homo sapiens |
| Matching Nucleotide Accession: | BC006411.1|Alignment |
| Category: | 84818 |
| Comment: | HS.129959 |
| Related Accession(s): | AF458065|Alignment || AK075534|Alignment || AK092907|Alignment || AK094746|Alignment || AK096824|Alignment || AY358840|Alignment || AY359098|Alignment || BC006411|Alignment |
| Gene Name: | interleukin 17 receptor C |
| Gene Definition: | Homo sapiens, interleukin 17 receptor C, mRNA (cDNA clone MGC:10763 IMAGE:3606276), complete cds. |
| Gene Symbol: | IL17RC |
| Summary: | This gene encodes a single-pass transmembrane protein that shares limited similarity with the interleukin-17 receptor. At least eleven alternatively spliced transcript variants of this gene have been detected. The full-length nature of five of the variants encoding distinct isoforms have been reported. |
| Expression: | Sage Tag Expression || Virtual Northern || Digital Expression Profile |
| Transcript Variant 1: | This variant (1) encodes the longest isoform (1). |
| Transcript Variant 2: | This variant (2) lacks an in-frame coding segment compared to variant 1. The resulting isoform (2) lacks an internal region, as compared to isoform 1. |
| Transcript Variant 3: | This variant (3) has multiple differences in the coding region compared to variant 1. The resulting isoform (3) lacks two internal regions and contains a distinct and shorter C-terminus, as compared to isoform 1. |
| Transcript Variant 4: | This variant (4) has multiple differences in the coding region compared to variant 1. The resulting isoform (4) lacks two internal regions and contains a distinct and shorter C-terminus, as compared to isoform 1. |
| Transcript Variant 5: | This variant (5) has multiple differences in the coding region compared to variant 1. The resulting isoform (5) lacks an internal region and contains a distinct and shorter C-terminus, as compared to isoform 1. The existence of this variant is supported by ESTs, but the predicted short ORF has not yet been experimentally confirmed. |
| mRNA Record: | NM_032732|Alignment || NM_153460|Alignment || NM_153461|Alignment || NM_153462|Alignment || NM_153463|Alignment |
| GO Category: molecular function | receptor activity (GO:0004872) |
| References: | GRIF: 84818 | PUBMED: IL17RC |
| ORF Information | |
| ORF length (bp): | 1617 |
| Sequence: | Nucleotide || Peptide || Translation || Quality Scores || Quality Scores with Sequence |
| Clone Information | |
| Collection Name: | Ultimate ORF Clones |
| Collection Type: | ORF Gateway™ Entry |
| Vector Name: | pENTR(tm)221 |
| Vector Antibiotic: | Kanamycin |
| Host Name: | E.coli |
| Protein | |
| Protein Accession: | AAM77569|Alignment || BAC11677|Alignment || BAC04001|Alignment || AAQ89199|Alignment || AAQ89456|Alignment || AAH06411|Alignment |
| Protein Record: | NP_116121|Alignment || NP_703190|Alignment || NP_703191|Alignment || NP_703192|Alignment || NP_703193|Alignment |
| Physical Properties: | (aa) || 0.0 (MW) || 0.0 (pI) |
| Protease Digestion: | Trypsin | Lys-C | Arg-C | Asp-N | V8-bicarb | V8-phosph | Chymotrypsin | CNBr |
| Predicted Secondary Structure: | View Secondary Structure |
| Protein Model Search: | Swiss-Model BLAST |
| Product: | interleukin 17 receptor C isoform 5 precursor |
| SNP Information | |
| SNP: | All rs in gene region | rs in coding region only | rs with heterozygosity only |
| SNP Map to: | Protein |
| Genomic Link | |
| LocusLink ID: | 84818 |
| Unigene ID: | Hs.129959 |
| Genome Alignment: | Map to Human Genome using BLAT || Map to Ensembl Genome Browser |
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Disclaimer: Invitrogen™ Corporation provides an evolving clone collection where each gene represented is identified as containing a complete open reading frame, based on a dynamic source of bioinformatic information contained within GenBank. GenBank is a genetic sequence database, which contains an annotated collection of all publicly available DNA sequences. Ultimate™ ORF Clones are typically derived from cDNA clones believed to contain a complete open reading frame, according to the most current GenBank update. Please note, subsequent GenBank updates may show some of these cDNA clones to contain a partial sequence, a non-coding sequence or other artifacts. Quarterly, Invitrogen™ Corporation will update the Ultimate™ ORF Clone Collection, by adding, deleting, or modifying the bioinformatic information to more accurately reflect the most current scientific information associated with each of the clones represented in the collection. It is highly recommended that the purchaser carefully evaluate the ORF clone sequence prior to purchase. It is the purchaser’s responsibility to check whether the sequence associated with any particular clone meets his/her scientific requirement prior to purchase. Invitrogen makes no warranties, express or implied, that the manufacture, use, importation, or sale of the gene contained within any Ultimate™ ORF clone will not infringe any third party intellectual property right. | |