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| Ultimate™ ORFCard for Clone ID IOH3289 | |
|---|---|
| Gene Information | |
| Clone ID: | IOH3289 |
| Organism: | Homo sapiens |
| Matching Nucleotide Accession: | NM_014624.3|Alignment |
| Category: | 6277 |
| Comment: | HS.275243 |
| Related Accession(s): | AY034480|Alignment || BX470102|Alignment || J02763|Alignment || M14300|Alignment || M18981|Alignment || BC001431|Alignment || BC009017|Alignment || BT006965|Alignment |
| Gene Name: | S100 calcium binding protein A6 (calcyclin) |
| Gene Definition: | Homo sapiens, S100 calcium binding protein A6 (calcyclin) (S100A6), mRNA |
| Gene Symbol: | S100A6 |
| Summary: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. |
| Expression: | Sage Tag Expression || Virtual Northern || Digital Expression Profile |
| mRNA Record: | NM_014624|Alignment |
| GO Category: biological process | axonogenesis (GO:0007409) cell proliferation (GO:0008283) cell-cell signaling (GO:0007267) positive regulation of fibroblast proliferation (GO:0048146) regulation of cell cycle (GO:0000074) |
| GO Category: cellular component | nuclear membrane (GO:0005635) |
| GO Category: molecular function | calcium ion binding (GO:0005509) growth factor activity (GO:0008083) protein binding (GO:0005515) |
| References: | GRIF: 6277 | PUBMED: S100A6 |
| ORF Information | |
| ORF length (bp): | 273 |
| Sequence: | Nucleotide || Peptide || Translation || Quality Scores || Quality Scores with Sequence |
| Clone Information | |
| Collection Name: | Ultimate ORF Clones |
| Collection Type: | ORF Gateway™ Entry |
| Vector Name: | pENTR(tm)221 |
| Vector Antibiotic: | Kanamycin |
| Host Name: | E.coli |
| Protein | |
| Protein Accession: | AAK59702|Alignment || CAI14752|Alignment || AAA51905|Alignment || AAA35886|Alignment || AAA51906|Alignment || AAH01431|Alignment || AAH09017|Alignment || AAP35611|Alignment || P06703|Alignment |
| Protein Record: | NP_055439|Alignment |
| Physical Properties: | (aa) || 0.0 (MW) || 0.0 (pI) |
| Protease Digestion: | Trypsin | Lys-C | Arg-C | Asp-N | V8-bicarb | V8-phosph | Chymotrypsin | CNBr |
| Predicted Secondary Structure: | View Secondary Structure |
| Protein Model Search: | Swiss-Model BLAST |
| OMIM: | 114110 |
| Product: | S100 calcium-binding protein A6 |
| SNP Information | |
| SNP: | All rs in gene region | rs in coding region only | rs with heterozygosity only |
| SNP Map to: | Protein |
| Genomic Link | |
| LocusLink ID: | 6277 |
| Unigene ID: | Hs.275243 |
| Genome Alignment: | Map to Human Genome using BLAT || Map to Ensembl Genome Browser |
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Disclaimer: Invitrogen™ Corporation provides an evolving clone collection where each gene represented is identified as containing a complete open reading frame, based on a dynamic source of bioinformatic information contained within GenBank. GenBank is a genetic sequence database, which contains an annotated collection of all publicly available DNA sequences. Ultimate™ ORF Clones are typically derived from cDNA clones believed to contain a complete open reading frame, according to the most current GenBank update. Please note, subsequent GenBank updates may show some of these cDNA clones to contain a partial sequence, a non-coding sequence or other artifacts. Quarterly, Invitrogen™ Corporation will update the Ultimate™ ORF Clone Collection, by adding, deleting, or modifying the bioinformatic information to more accurately reflect the most current scientific information associated with each of the clones represented in the collection. It is highly recommended that the purchaser carefully evaluate the ORF clone sequence prior to purchase. It is the purchaser’s responsibility to check whether the sequence associated with any particular clone meets his/her scientific requirement prior to purchase. Invitrogen makes no warranties, express or implied, that the manufacture, use, importation, or sale of the gene contained within any Ultimate™ ORF clone will not infringe any third party intellectual property right. | |