* The ORFCard has links to several external public sites for your convenience.
These links may be occasionally unavailable.
| Ultimate™ ORFCard for Clone ID IOH29205 | |
|---|---|
| Gene Information | |
| Clone ID: | IOH29205 |
| Organism: | Homo sapiens |
| Matching Nucleotide Accession: | BC059400.1|Alignment |
| Category: | 9586 |
| Comment: | HS.437075 |
| Related Accession(s): | AC005105|Alignment || AB209262|Alignment || BC059400|Alignment || L05515|Alignment || L05911|Alignment || L05912|Alignment || L05913|Alignment |
| Gene Name: | cAMP responsive element binding protein 5 |
| Gene Definition: | Homo sapiens, cAMP responsive element binding protein 5, mRNA, complete cds. |
| Gene Symbol: | CREB5 |
| Summary: | The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Expression: | Sage Tag Expression || Virtual Northern || Digital Expression Profile |
| Transcript Variant 1: | This variant (1) represents the longest transcript, and encodes the longest isoform (alpha). |
| Transcript Variant 2: | This variant (2) differs in the 5' UTR and the 5' coding region, compared to variant 1. The resulting isoform (beta) has a shorter N-terminus when compared to isoform alpha. |
| Transcript Variant 3: | This variant (3) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (gamma) has a shorter N-terminus when compared to isoform alpha. |
| Transcript Variant 4: | This variant (4) differs in the 5' UTR and the 5' coding region, compared to variant 1. The resulting isoform (delta) contains a distinct N-terminus, compared to isoform alpha. |
| mRNA Record: | NM_001011666|Alignment || NM_004904|Alignment || NM_182898|Alignment || NM_182899|Alignment |
| GO Category: biological process | positive regulation of transcription, DNA-dependent (GO:0045893) regulation of transcription, DNA-dependent (GO:0006355) transcription (GO:0006350) transcription from RNA polymerase II promoter (GO:0006366) |
| GO Category: cellular component | nucleus (GO:0005634) nucleus (GO:0005634) |
| GO Category: molecular function | DNA binding (GO:0003677) protein binding (GO:0005515) transcription factor activity (GO:0003700) zinc ion binding (GO:0008270) |
| References: | GRIF: 9586 | PUBMED: CREB5 |
| ORF Information | |
| ORF length (bp): | 1005 |
| Sequence: | Nucleotide || Peptide || Translation || Quality Scores || Quality Scores with Sequence |
| Clone Information | |
| Collection Name: | Ultimate ORF Clones |
| Collection Type: | ORF Gateway™ Entry |
| Vector Name: | pENTR(tm)221 |
| Vector Antibiotic: | Kanamycin |
| Host Name: | E.coli |
| Protein | |
| Protein Accession: | AAP22329|Alignment || BAD92499|Alignment || AAH59400|Alignment || AAA52072|Alignment || AAC37525|Alignment || AAC37527|Alignment || AAC37526|Alignment || Q02930|Alignment |
| Protein Record: | NP_001011666|Alignment || NP_004895|Alignment || NP_878901|Alignment || NP_878902|Alignment |
| Physical Properties: | (aa) || 0.0 (MW) || 0.0 (pI) |
| Protease Digestion: | Trypsin | Lys-C | Arg-C | Asp-N | V8-bicarb | V8-phosph | Chymotrypsin | CNBr |
| Predicted Secondary Structure: | View Secondary Structure |
| Protein Model Search: | Swiss-Model BLAST |
| Product: | cAMP responsive element binding protein 5 isoform gamma |
| SNP Information | |
| SNP: | All rs in gene region | rs in coding region only | rs with heterozygosity only |
| SNP Map to: | Protein |
| Genomic Link | |
| LocusLink ID: | 9586 |
| Unigene ID: | Hs.437075 |
| Genome Alignment: | Map to Human Genome using BLAT || Map to Ensembl Genome Browser |
|
Disclaimer: Invitrogen™ Corporation provides an evolving clone collection where each gene represented is identified as containing a complete open reading frame, based on a dynamic source of bioinformatic information contained within GenBank. GenBank is a genetic sequence database, which contains an annotated collection of all publicly available DNA sequences. Ultimate™ ORF Clones are typically derived from cDNA clones believed to contain a complete open reading frame, according to the most current GenBank update. Please note, subsequent GenBank updates may show some of these cDNA clones to contain a partial sequence, a non-coding sequence or other artifacts. Quarterly, Invitrogen™ Corporation will update the Ultimate™ ORF Clone Collection, by adding, deleting, or modifying the bioinformatic information to more accurately reflect the most current scientific information associated with each of the clones represented in the collection. It is highly recommended that the purchaser carefully evaluate the ORF clone sequence prior to purchase. It is the purchaser’s responsibility to check whether the sequence associated with any particular clone meets his/her scientific requirement prior to purchase. Invitrogen makes no warranties, express or implied, that the manufacture, use, importation, or sale of the gene contained within any Ultimate™ ORF clone will not infringe any third party intellectual property right. | |