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| Ultimate™ ORFCard for Clone ID IOH27982 | |
|---|---|
| Gene Information | |
| Clone ID: | IOH27982 |
| Organism: | Homo sapiens |
| Matching Nucleotide Accession: | BC039235.1|Alignment |
| Category: | 213 |
| Comment: | HS.418167 |
| Related Accession(s): | M12523|Alignment || M13075|Alignment || S69192|Alignment || S70799|Alignment || AF116645|Alignment || AF130077|Alignment || AF190168|Alignment || AF542069|Alignment || AY358313|Alignment || AY728024|Alignment || AY960291|Alignment || BC014308|Alignment || BC034023|Alignment || BC034026|Alignment || BC035969|Alignment || BC036003|Alignment || BC039235|Alignment || BC041789|Alignment || CR749331|Alignment || V00494|Alignment || V00495|Alignment || A06977|Alignment |
| Gene Name: | albumin |
| Gene Definition: | Homo sapiens, albumin, mRNA, containing frame-shift errors |
| Gene Symbol: | ALB |
| Summary: | Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. The human albumin gene is 16,961 nucleotides long from the putative 'cap' site to the first poly(A) addition site. It is split into 15 exons which are symmetrically placed within the 3 domains that are thought to have arisen by triplication of a single primordial domain. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. |
| Expression: | Sage Tag Expression || Virtual Northern || Digital Expression Profile |
| mRNA Record: | NM_000477|Alignment |
| GO Category: biological process | body fluid osmoregulation (GO:0050891) negative regulation of non-apoptotic programmed cell death (GO:0043072) transport (GO:0006810) transport (GO:0006810) water homeostasis (GO:0030104) |
| GO Category: cellular component | extracellular space (GO:0005615) |
| GO Category: molecular function | antioxidant activity (GO:0016209) carrier activity (GO:0005386) copper ion binding (GO:0005507) drug binding (GO:0008144) fatty acid binding (GO:0005504) water binding (GO:0050824) |
| References: | GRIF: 213 | PUBMED: ALB |
| ORF Information | |
| ORF length (bp): | 1884 |
| Sequence: | Nucleotide || Peptide || Translation || Quality Scores || Quality Scores with Sequence |
| Clone Information | |
| Collection Name: | Ultimate ORF Clones |
| Collection Type: | ORF Gateway™ Entry |
| Vector Name: | pENTR(tm)221 |
| Vector Antibiotic: | Kanamycin |
| Host Name: | E.coli |
| Protein | |
| Protein Accession: | AAA98797|Alignment || AAA98798|Alignment || AAA51688|Alignment || AAB30282|Alignment || AAB31177|Alignment || AAF71067|Alignment || AAG35503|Alignment || AAF01333|Alignment || AAN17825|Alignment || AAQ89947|Alignment || AAU21642|Alignment || AAX63425|Alignment || AAH14308|Alignment || AAH34023|Alignment || AAH35969|Alignment || AAH36003|Alignment || AAH39235|Alignment || AAH41789|Alignment || CAH18185|Alignment || CAA23753|Alignment || CAA23754|Alignment || P02768|Alignment || CAA00606|Alignment |
| Protein Record: | NP_000468|Alignment |
| Physical Properties: | (aa) || 0.0 (MW) || 0.0 (pI) |
| Protease Digestion: | Trypsin | Lys-C | Arg-C | Asp-N | V8-bicarb | V8-phosph | Chymotrypsin | CNBr |
| Predicted Secondary Structure: | View Secondary Structure |
| Protein Model Search: | Swiss-Model BLAST |
| OMIM: | 103600 |
| Product: | albumin precursor |
| SNP Information | |
| SNP: | All rs in gene region | rs in coding region only | rs with heterozygosity only |
| SNP Map to: | Protein |
| Genomic Link | |
| LocusLink ID: | 213 |
| Unigene ID: | Hs.418167 |
| Genome Alignment: | Map to Human Genome using BLAT || Map to Ensembl Genome Browser |
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Disclaimer: Invitrogen™ Corporation provides an evolving clone collection where each gene represented is identified as containing a complete open reading frame, based on a dynamic source of bioinformatic information contained within GenBank. GenBank is a genetic sequence database, which contains an annotated collection of all publicly available DNA sequences. Ultimate™ ORF Clones are typically derived from cDNA clones believed to contain a complete open reading frame, according to the most current GenBank update. Please note, subsequent GenBank updates may show some of these cDNA clones to contain a partial sequence, a non-coding sequence or other artifacts. Quarterly, Invitrogen™ Corporation will update the Ultimate™ ORF Clone Collection, by adding, deleting, or modifying the bioinformatic information to more accurately reflect the most current scientific information associated with each of the clones represented in the collection. It is highly recommended that the purchaser carefully evaluate the ORF clone sequence prior to purchase. It is the purchaser’s responsibility to check whether the sequence associated with any particular clone meets his/her scientific requirement prior to purchase. Invitrogen makes no warranties, express or implied, that the manufacture, use, importation, or sale of the gene contained within any Ultimate™ ORF clone will not infringe any third party intellectual property right. | |