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| Ultimate™ ORFCard for Clone ID IOH14745 | |
|---|---|
| Gene Information | |
| Clone ID: | IOH14745 |
| Organism: | Homo sapiens |
| Matching Nucleotide Accession: | BC024289.1|Alignment |
| Category: | 2537 |
| Comment: | HS.510635 |
| Related Accession(s): | AL445490|Alignment || CQ834276|Alignment || U22970|Alignment || AK024814|Alignment || BC011601|Alignment || BC015603|Alignment || BN000257|Alignment || BT006850|Alignment || X02492|Alignment |
| Gene Name: | interferon, alpha-inducible protein (clone IFI-6-16) |
| Gene Definition: | Homo sapiens, interferon, alpha-inducible protein 6, mRNA (cDNA clone MGC:39273 IMAGE:5440834), complete cds. |
| Gene Symbol: | G1P3 |
| Summary: | This gene is an interferon-stimulated gene (ISG). The type I- (alpha and beta) interferons induce transcription while type II- (gamma) interferon is a poor transcription inducer for this gene. A minisatellite repeat region, of varying lengths, has been found at the end of exon 2 and the beginning of intron 2. Alternative splicing occurs due to the use of alternative splice donor sites provided by the minisatellite sequence. Three alternatively spliced transcript variants have been described. The encoded product is a hydrophobic protein and thought to be present in the membrane. It is postulated to be a precursor protein but its signal peptide region has not been confirmed. The function of the encoded protein has not been determined. |
| Expression: | Sage Tag Expression || Virtual Northern || Digital Expression Profile |
| Transcript Variant 1: | This variant (1) contains an exon 2 minisatellite sequence of 3 bases and encodes the shortest isoform (a). |
| Transcript Variant 2: | This variant (2) contains an exon 2 minisatellite sequence of 15 bases. This variant encodes a longer isoform (b) compared to isoform a. |
| Transcript Variant 3: | This variant (3) contains an exon 2 minisatellite sequence of 27 bases. This variant encodes the longest isoform (c) compared to isoform a. |
| mRNA Record: | NM_002038|Alignment || NM_022872|Alignment || NM_022873|Alignment |
| GO Category: biological process | immune response (GO:0006955) response to pest, pathogen or parasite (GO:0009613) |
| GO Category: cellular component | integral to membrane (GO:0016021) |
| References: | GRIF: 2537 | PUBMED: G1P3 |
| ORF Information | |
| ORF length (bp): | 1416 |
| Sequence: | Nucleotide || Peptide || Translation || Quality Scores || Quality Scores with Sequence |
| Clone Information | |
| Collection Name: | Ultimate ORF Clones |
| Collection Type: | ORF Gateway™ Entry |
| Vector Name: | pENTR(tm)221 |
| Vector Antibiotic: | Kanamycin |
| Host Name: | E.coli |
| Protein | |
| Protein Accession: | CAH72020|Alignment || CAH72021|Alignment || CAH72022|Alignment || CAH05353|Alignment || AAC50159|Alignment || AAC50160|Alignment || AAC50161|Alignment || AAH11601|Alignment || AAH15603|Alignment || CAE12275|Alignment || AAP35496|Alignment || CAA26322|Alignment || P09912|Alignment |
| Protein Record: | NP_002029|Alignment || NP_075010|Alignment || NP_075011|Alignment |
| Physical Properties: | (aa) || 0.0 (MW) || 0.0 (pI) |
| Protease Digestion: | Trypsin | Lys-C | Arg-C | Asp-N | V8-bicarb | V8-phosph | Chymotrypsin | CNBr |
| Predicted Secondary Structure: | View Secondary Structure |
| Protein Model Search: | Swiss-Model BLAST |
| OMIM: | 147572 |
| Product: | interferon induced 6-16 protein isoform c |
| SNP Information | |
| SNP: | All rs in gene region | rs in coding region only | rs with heterozygosity only |
| SNP Map to: | Protein |
| Genomic Link | |
| LocusLink ID: | 2537 |
| Unigene ID: | Hs.523847 |
| Genome Alignment: | Map to Human Genome using BLAT || Map to Ensembl Genome Browser |
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Disclaimer: Invitrogen™ Corporation provides an evolving clone collection where each gene represented is identified as containing a complete open reading frame, based on a dynamic source of bioinformatic information contained within GenBank. GenBank is a genetic sequence database, which contains an annotated collection of all publicly available DNA sequences. Ultimate™ ORF Clones are typically derived from cDNA clones believed to contain a complete open reading frame, according to the most current GenBank update. Please note, subsequent GenBank updates may show some of these cDNA clones to contain a partial sequence, a non-coding sequence or other artifacts. Quarterly, Invitrogen™ Corporation will update the Ultimate™ ORF Clone Collection, by adding, deleting, or modifying the bioinformatic information to more accurately reflect the most current scientific information associated with each of the clones represented in the collection. It is highly recommended that the purchaser carefully evaluate the ORF clone sequence prior to purchase. It is the purchaser’s responsibility to check whether the sequence associated with any particular clone meets his/her scientific requirement prior to purchase. Invitrogen makes no warranties, express or implied, that the manufacture, use, importation, or sale of the gene contained within any Ultimate™ ORF clone will not infringe any third party intellectual property right. | |